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diflunisal (dolobid)

available over the counter: no

uses: mild to moderate pain and inflammation caused by tendinitis, arthritis, soft tissue injuries,

mechanism of action: interferes with formation of prostaglandins ( cause inflammation and make nerves more sensitive)

side effects

  • commom: nausea, vomiting, heartburn, diarrhea, constipation, headache
  • less common:
    • ulcers or sores in mouth, rashes or blistering of skin, ringing sound in ears, tingling of hands or feet, seizures, blurred vision

concerns: inhibits blood coagulation, and may increase bleeding at surgery;  stop meds well before surgery


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