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etodolac (lodine)

available over the counter: no

uses: treatment of mild to moderate pain and inflammation from tendinitis, arthritis, bursitis, gout, soft tissue injuries, migraines, vascular headaches, menstrual cramps

mechanism of action: interferes with the formation of prostaglandins, which cause inflammation and sensitize nerves to pain impulses

side effects
• commom:
nausea, vomiting, diarrhea, constipation, headache
• less common: sores in mouth, depression, rashes, ringing in ears, blurred vision
• serious: shortness of breath, swelling of legs, ulcers, tarry stools

concerns: may interfere with blood coagulation (stop 3 days before surgery); prolonged use may cause gastrointestinal problems, ulcers, bleeding, kidney and liver dysfunction


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