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piroxicam (feldene)

available over the counter: no

uses: mild to moderate pain and inflammation caused by tendinitis, arthritis, bursitis, bout, soft tissue injury, migraines, vascular headaches, menstrual cramps

mechanism of action: interferes with formation of prostaglandins ( cause inflammation and make nerves more sensitive)

side effects
• common:
nausea, vomiting, heartburn, diarrhea, constipation, headache
• less common: ulcers or sores in mouth, rashes or blistering of skin, ringing sound in ears, tingling of hands or feet, seizures, blurred vision
• serious: shortness of breath, wheezing, chest pain, peptic ulcer disease, kidney failure

concerns: inhibits blood coagulation, and may increase bleeding at surgery;  stop meds 3 days before surgery; prolonged use may cause gastrointestinal problems, ulcers, kidney and liver dysfunction


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