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ranitidine (zantac)

available over the counter: no

uses: treatment of duodenal ulcers caused by infection with Helicobacter pylori bacteria

mechanism of action: enhances antibiotic effect of clarithromycin to erradicate Helicobacter pylori bacteria, which is felt to re causative of the majority of peptic ulcers

side effects
• common:
diarrhea, nausea, vomiting, headache,
• less common: abdominal discomfort, tremors
• serious: none

concerns: patients not successfully treated with ranitidine and clarithromycin may have Helicobacter pylori resistant to the medicines


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